Title

Spectroscopic Assay Development in Drug Development

Presenter

Cole Phalen

Abstract

This past summer (2015) I worked in the Tuberculosis Drug Discovery group at the Infectious Disease Research Institute (IDRI) in Seattle, Washington. IDRI had already identified a potential drugable target enzyme that produces pyrophosphate (PPi) as a side product. Our project was designed to figure out a novel way to monitor the release of PPi and be able to do so in a 384-well plate format. Once complete, our chosen technique (using either UV or fluorescent techniques) would enable IDRI to test a suite of potential drugs they received from a corporate partnership.

Faculty Sponsor

James Russo

Sponsor Department/Programs

Biochemistry, Biophysics and Molecular Biology

Tracks

Poster Session

Location

Cordiner Hall

Presentation Type

Poster

Research Funding Source or OCS Program

Infectious Disease Research Institute (IDRI)

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Apr 19th, 1:00 PM Apr 19th, 2:00 PM

Spectroscopic Assay Development in Drug Development

Cordiner Hall

This past summer (2015) I worked in the Tuberculosis Drug Discovery group at the Infectious Disease Research Institute (IDRI) in Seattle, Washington. IDRI had already identified a potential drugable target enzyme that produces pyrophosphate (PPi) as a side product. Our project was designed to figure out a novel way to monitor the release of PPi and be able to do so in a 384-well plate format. Once complete, our chosen technique (using either UV or fluorescent techniques) would enable IDRI to test a suite of potential drugs they received from a corporate partnership.