Development of palladium-catalyzed cross-coupling reactions for the CB₁₁⁻ carborane

    Item Description
    Linked Agent
    Creator (cre): Raffman, Ethan
    Advisor (adv): Juhasz, Mark
    May 19, 2020
    Graduation Year

    Previous work in the Juhasz Lab had explored the palladium catalyzed Kumada coupling as a method to functionalize the 1-carba-closo-dodecaborate(-) anion (also known as CB₁₁⁻) at the 12-boron vertex. In this presented research, several other palladium catalyzed reactions were tested to varying degrees of success. A Suzuki-style coupling with arylboronic acids failed to produce any desired product. A Heck-type coupling had high turnover of starting material into desired product but with moderate quantities of inseparable byproducts. A novel reaction that used a palladium catalyst and silver acetate to put an acetyl group on the cluster was also discovered and explored. These findings offer new insights to the reactivity of the CB₁₁⁻ cluster and future strategies for synthesizing derivatives.

    71 pages
    Contact Us

    If you have questions about permitted uses of this content, please contact the Arminda administrator: