Using QPCR to screen for the onset of morphological plasticity in the rat model of brain information storage
May 11, 2011
Department or Program
Biochemistry, Biophysics and Molecular Biology
The quantitative PCR technique offers an analysis of the molecular regulation of cell growth that leads to morphological changes in the brain. This study examines the regulation of three genes, Egr-1, GFAP, and VEGF, that are implicated in neuronal, astrocytic, and vascular plasticity in the visual cortex and hippocampus and serve as markers for the onset of morphological plasticity.