Jeremy Guggenheim

Graduation Year


Date of Thesis Acceptance

Fall 5-11-2011

Major Department or Program



Kate Jackson


This thesis examines the effects of astrocytes on dendritic development by way of a long standing in vitro model. Research conducted for this thesis showed that physical contact with astrocytes minimizes dendritic growth as measured by Sholl ring analysis, but simultaneously seems to promote branching as measured by branch analysis. This thesis places these findings in the broader context of contemporary astrocyte research, in particular by striving to explain how the findings are compatible with the current understanding of astrocytes in the developing brain.

Page Count


Subject Headings

Rats as laboratory animals, Astrocytes, Synapses, Hippocampus (Brain), Neurons, Rats --Fetuses, Dendrites -- Growth and development, Whitman College -- Dissertation collection 2011 -- Biology Department

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Document Type

Public Accessible Thesis

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Biology Commons



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